| Type | MGI:General | Description | 2-3 days after injection of 1.25ng/g body weight or higher of the immunotoxin LMB2 transgenic mice develop nonselective proteinuria, with proteinuria developing more rapidly with higher doses; wild-type or untreated transgenic mice show no abnormal morphological or physiological phenotype at a dose of 0.625 ng/g toxin, proteinuria peaks at day 7 and returns to normal range by 28 days |
