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Allele : Ankdd1a<em1(IMPC)J> ankyrin repeat and death domain containing 1A; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:7545158 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Ankdd1a
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CACTAACCTGCCCTACCCCA and ATACAAGTGATACAGAACCT, which resulted in a 320 bp deletion beginning at Chromosome 9 position 65,503,339 bp and ending after 65,503,658 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000246940 (exon 12) and 172 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 367 and early truncation 76 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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2 Publication categories

Trail: Allele