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Protein Coding Gene : Dcaf8 DDB1 and CUL4 associated factor 8
Primary Identifier  MGI:91860 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  98193
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to be located in cytosol; mitochondrion; and nucleoplasm. Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Predicted to be active in cytoplasm. Is expressed in several structures, including brain; liver; lung; metanephros; and spleen. Human ortholog(s) of this gene implicated in giant axonal neuropathy 2. Orthologous to human DCAF8 (DDB1 and CUL4 associated factor 8).
  • synonyms:
  • AA433120,
  • MGI:2138099,
  • WD repeat domain 42A,
  • DNA segment, Chr 1, University of California at Los Angeles 4,
  • D1Dau35e,
  • expressed sequence AU018973,
  • MGI:1888988,
  • AU018973,
  • MGI:2138088,
  • DDB1 and CUL4 associated factor 8,
  • EST AA792214,
  • AA792214,
  • Wdr42a,
  • expressed sequence C76055,
  • MGI:1347003,
  • MGD-MRK-5719,
  • expressed sequence AA433120,
  • MGI:2138650,
  • MGI:2138429,
  • expressed sequence AA408877,
  • DNA segment, Chr 1, DA Underhill 35, expressed,
  • AA408877,
  • Dcaf8,
  • D1Ucla4,
  • H326,
  • C76055
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Features --> Cross References

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2 Involved In Mutations

Trail: ProteinCodingGene

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

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Function

Mouse features --> Functions (GO terms)

Homology

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Interactions

3 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

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