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Protein Domain : HAUS augmin-like complex subunit 4

Primary Identifier  IPR029327 Type  Family
Short Name  HAUS4
description  HAUS4 is part of the HAUS augmin-like complex, which contributes to mitotic spindle assembly, maintenance of chromosome integrity and completion of cytokinesis [, ].Human augmin complex is composed of 8 subunits and interacts with the gamma-tubulin ring complex (gamma-TuRC) in centrosomes []. This interaction affects MT generation during mitosis and is critical for chromosome segregation and cytokinesis in human cells []. Similar to humans, Arabidopsis augmin complex also contains 8 subunits, including AUGMIN subunit 4 (AUG4) in this entry []. Despite lacking cetrosomes, the augmin complex in Arabidopsis also plays an important part in gamma-tubulin-dependent MT nucleation and the assembly of microtubule arrays during mitosis [].

1 Child Features

0 Parent Features

6 Protein Domain Regions