Primary Identifier | MGI:6781648 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Hecw1 |
Transmission | Germline | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Using homologous recombination in ES cells, the targeting construct inserted FRT-IRES-LacZ-Loxp-neo-FRT-LoxP into the intron upstream of the exon 8, and an additional LoxP was inserted into the intron downstream of the exon 8. A cre mediated deletion removed neo-cassette-FRT-LoxP and exon 8 leaving FRT-IRES-LacZ-LoxP in the intron. |