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Allele : Sigirr<tm1Lix> single immunoglobulin and toll-interleukin 1 receptor (TIR) domain; targeted mutation 1, Xiaoxia Li
Primary Identifier  MGI:2675236 Allele Type  Targeted
Attribute String  Null/knockout Gene  Sigirr
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 2 through 5 were replaced with a neomycin selection cassette inserted by homologous recombination. The insertion of neo was reported to generate stop codons in all three reading frames. Endogenous transcript was undetected by Northern blot analysis of homozygous mutant kidney tissue.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Sigirr<->,
  • Sigirr<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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