| Primary Identifier | IPR027857 | Type | Family |
| Short Name | SCRE |
| description | This entry represents the Protein SPO16 homologue (SPO16, also known as Synaptonemal complex reinforcing element SCRE), including the mammalian orthologue of budding yeast Spo16. It plays a key role in reinforcing the integrity of the central element of the synaptonemal complex (SC), resulting in the SC stabilization which ensures the progression of meiotic prophase I in male and female germ cells [. It promotes homologous recombination and crossing-over in meiotic prophase I via its association with SHOC1 []. It is also required for the localization of TEX11 and MSH4 to recombination intermediates []. |
