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Publication : The mouse as a model for human audition. A review of the literature.

First Author  Henry KR Year  1992
Journal  Audiology Volume  31
Issue  4 Pages  181-9
PubMed ID  1444929 Mgi Jnum  J:2851
Mgi Id  MGI:51371 Doi  10.3109/00206099209081653
Citation  Henry KR, et al. (1992) The mouse as a model for human audition. A review of the literature. Audiology 31(4):181-9
abstractText  The mouse has several distinct advantages as an experimental model for human audition. Mice and humans express a similar presbyacusic and ototraumatic pattern. Several genetic mouse models also exist for conditions resembling human auditory disorders, such as otosclerosis. This paper reviews the strains of inbred mice (e.g. the CBA/J) which have recently been used as models for the normal human auditory system, describing their deficiencies. It is suggested that the F1 offspring of CBA/CaJ and AU/SsJ inbred mice would have advantages over existing models.
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