Primary Identifier | MGI:3665312 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Gabpa |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | LoxP sites were introduced into introns 7 and 9 and and frt-flanked neomycin resistance cassette was inserted within the loxP-flanked region in intron 9. The neomycin resistance cassette was removed by crossing to Flp- expressing mice, leaving only the loxP sites that flank sequences corresponding to the DNA-binding region of the encoded protein. |