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Protein Coding Gene : Prps2 phosphoribosyl pyrophosphate synthetase 2
Primary Identifier  MGI:97776 Organism  mouse, laboratory
Chromosome  X NCBI Gene Number  110639
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables ribose phosphate diphosphokinase activity. Involved in 5-phosphoribose 1-diphosphate biosynthetic process and pentose-phosphate shunt. Is active in cytosol. Is expressed in alimentary system; central nervous system; and retina. Orthologous to human PRPS2 (phosphoribosyl pyrophosphate synthetase 2).
PHENOTYPE: Males hemizygous for a null allele show altered B cell physiology with a minor decrease in rates of purine nucleotide biosynthesis. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-13630,
  • AA589463,
  • Prps-2,
  • MGI:2147895,
  • MGC:28388,
  • MGI:2147833,
  • 2610101M19Rik,
  • Prps2,
  • expressed sequence AI464149,
  • AI464149,
  • expressed sequence AA589463,
  • RIKEN cDNA 2610101M19 gene,
  • MGI:1915547,
  • phosphoribosyl pyrophosphate synthetase 2,
  • MGD-MRK-13632
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Trail: ProteinCodingGene

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