Primary Identifier | MGI:4442899 | Allele Type | Chemically induced (ENU) |
Gene | Tyr | Inheritance Mode | Recessive |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false | Project Collection | Beutler Mutagenetix |
molecularNote | The mutation comprises a T-to-A transversion at coding nucleotide 1280 of mRNA NM_011661, in the fourth of the gene's five exons (Chr7:87438023 GRCm38). It causes replacement of valine by aspartic acid at amino acid 427 of the tyrosinase protein (p.V427D). |