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Allele : P4ha1<tm1Jomy> procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide; targeted mutation 1, Johanna Myllyharju

Primary Identifier  MGI:3706369 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  P4ha1
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 2 is replaced by a lacZ/neo cassette. RT-PCR analysis confirmed the absence of mRNA in homozygous embryos at E10.5. Enzymatic activity, as determined in an activity assay with radioactively-labeled substrate, was reduced to 20% of normal activity.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

10 Publication categories