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Protein Coding Gene : Ppp1r12a protein phosphatase 1, regulatory subunit 12A
Primary Identifier  MGI:1309528 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  17931
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable several functions, including 14-3-3 protein binding activity; phosphatase regulator activity; and protein kinase binding activity. Acts upstream of or within cellular response to xenobiotic stimulus and regulation of nucleocytoplasmic transport. Located in A band and Z disc. Is expressed in several structures, including corpus striatum; genital tubercle epithelium; head mesenchyme; urethra epithelium; and urothelium. Orthologous to human PPP1R12A (protein phosphatase 1 regulatory subunit 12A).
PHENOTYPE: Homozygous null mice die before E7.5. Mice homozygous for a smooth muscle specific conditional knockout exhibit altered intestinal smooth muscle contractility. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 5730577I22 gene,
  • RIKEN cDNA 1200015F06 gene,
  • protein phosphatase 1, regulatory subunit 12A,
  • Ppp1r12a,
  • Mypt1,
  • MGI:2143509,
  • DNA segment, Chr 10, ERATO Doi 625, expressed,
  • myosin phosphatase, target subunit 1,
  • MGI:2143782,
  • expressed sequence AA792106,
  • 1200015F06Rik,
  • AA792106,
  • AV099298,
  • MGI:1918986,
  • MGI:1289205,
  • MGI:1917922,
  • expressed sequence AV099298,
  • 5730577I22Rik,
  • D10Ertd625e
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