| Primary Identifier | MGI:1330348 | Organism | mouse, laboratory |
| Chromosome | 3 | Mgi Type | polymorphic pseudogene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable lipid binding activity. Predicted to be a structural constituent of skin epidermis. Acts upstream of or within response to estradiol. Located in cytoplasm and nucleus. Is expressed in epidermis; epidermis cornified layer; and skin. Orthologous to several human genes including SPRR2A (small proline rich protein 2A); SPRR2B (small proline rich protein 2B); and SPRR2D (small proline rich protein 2D). |
| specificity | This gene is a member of a tandemly arrayed set of genes that encode small proline-rich proteins, which are involved in epidermal barrier formation and are upregulated under stress conditions. While expression of this gene has been demonstrated, a reference genome insertion would disrupt its open reading frame, and it is thus classified as a transcribed pseudogene. However, transcripts without this insertion have also been described, and these would potentially encode a small proline-rich protein. [provided by RefSeq, Jul 2008] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
