|  Help  |  About  |  Contact Us

Protein Coding Gene : Matk megakaryocyte-associated tyrosine kinase

Primary Identifier  MGI:99259 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  17179
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable non-membrane spanning protein tyrosine kinase activity. Predicted to be located in cytoplasm and membrane. Predicted to be active in plasma membrane. Is expressed in brain; gonad; hemolymphoid system gland; and intestine. Orthologous to human MATK (megakaryocyte-associated tyrosine kinase).
PHENOTYPE: Homozygous mice are viable and fertile and appear normal. Unchallenged mutant mice exhibit no hematopoietic defects. SPKLS cell numbers are elevated. IL-7 induced BM cell proliferation and pre-B cell colony formation are enhanced. Antigen induced IFN-gamma secretion is reduced. [provided by MGI curators]
  • synonyms:
  • Matk,
  • Ntk,
  • HYL,
  • MGD-MRK-16018,
  • CHK,
  • megakaryocyte-associated tyrosine kinase,
  • Csk homologous kinase

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For