| First Author | Okumura A | Year | 1996 |
| Journal | J Virol | Volume | 70 |
| Issue | 6 | Pages | 4146-9 |
| PubMed ID | 8648758 | Mgi Jnum | J:52540 |
| Mgi Id | MGI:1329738 | Doi | 10.1128/jvi.70.6.4146-4149.1996 |
| Citation | Okumura A, et al. (1996) Maintenance of pluripotency in mouse embryonic stem cells persistently infected with murine coronavirus. J Virol 70(6):4146-9 |
| abstractText | A persistently coronavirus-infected embryonic stem (ES) cell line A3/MHV was established by infecting an ES cell line, A3-1, with mouse hepatitis virus type-2. Although almost all A3/MHV cells were found infected, both A3/MHV and A3-1 cells expressed comparable levels of cell surface differentiation markers. In addition, A3/MHV cells retained the ability to form embryoid bodies. These results suggest that persistent coronavirus infection does not affect the differentiation of ES cells. |
