| Primary Identifier | MGI:1334255 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 19158 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables guanyl-nucleotide exchange factor activity and inositol 1,4,5 trisphosphate binding activity. Predicted to be involved in negative regulation of dendrite development. Predicted to act upstream of or within regulation of cell adhesion. Located in bicellular tight junction. Is active in glutamatergic synapse and postsynapse. Is expressed in brain and spinal cord. Orthologous to human CYTH2 (cytohesin 2). PHENOTYPE: Mice homozygous for a conditional allele activated in Schwann cell exhibit reduced sciatic nerve myelin sheath thickness. Mice homozygous for a null allele exhibit reduced eosinophilic infiltration into the septum an ovalbumin-induced model of murine rhinitis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
