Primary Identifier | MGI:1855696 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 53603 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables cytokine activity. Acts upstream of or within signal transduction. Is active in extracellular space. Is expressed in ileum; male reproductive gland or organ; and skin. Orthologous to human TSLP (thymic stromal lymphopoietin). PHENOTYPE: Mice homozygous for a knock-out allele exhibit resistance to MC903-induced atopic dermatitis. Mice homozygous for another knock-out allele exhibit altered airway inflammation induced by LPS. [provided by MGI curators] |