Primary Identifier | MGI:4438958 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(TG-TSHR)50.6Smcl |
Strain of Origin | (BALB/c x C57BL/6)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | This transgene expresses the human TSHR alpha-subunit cDNA (amino acid residues 1-289) with a 6-histidine tag under the control of the bovine thyroglobulin promoter. Human TSHR alpha-subunit expression, analyzed by RT-PCR, is detected in thyroid tissue from transgenic mice. Lines 51.9 and 60.6 were also generated. |