| Type | MGI:General | Description | in a T cell-transfer model of chronic colitis, Rag1 null mice reconstituted with naive T cells (CD4+CD45RBhighCD25low) exhibit higher colitis clinical scores, increased infiltration of mononuclear cells in colonic lamina propria, more severe destruction of the epithelial barrier, and significantly more alpha4+ CD4+ T cells in the colon than control mice receiving wild-type naive T cells |
