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Publication : Dynamic pattern of mRNA expression of plasticity-related gene-3 (PRG-3) in the mouse cerebral cortex during development.

First Author  Wang WZ Year  2005
Journal  Brain Res Bull Volume  66
Issue  4-6 Pages  454-60
PubMed ID  16144631 Mgi Jnum  J:106347
Mgi Id  MGI:3618305 Doi  10.1016/j.brainresbull.2005.05.010
Citation  Wang WZ, et al. (2005) Dynamic pattern of mRNA expression of plasticity-related gene-3 (PRG-3) in the mouse cerebral cortex during development. Brain Res Bull 66(4-6):454-60
abstractText  Intrinsic genetic differences and extrinsic influences both contribute to the formation of functional and anatomical areas within the mammalian cerebral cortex. Using subtractive hybridisation and differential screening, we demonstrated that plasticity-related gene-3 (PRG-3) is differentially expressed between the dorsal and lateral cortex at P6. PRG-3 is one of the key enzymes that are involved in the metabolism of phospholipids, such as LPA and S1P, in the nervous system. Here, for the first time, we report the mRNA expression pattern of PRG-3 in the developing and adult mouse cerebral cortex.
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