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Publication : Identification of amino-acid polymorphism within the leucine zipper motif of mouse transcription factor A1.

First Author  Kajimoto Y Year  1994
Journal  Gene Volume  139
Issue  2 Pages  247-9
PubMed ID  8112613 Mgi Jnum  J:17006
Mgi Id  MGI:65062 Doi  10.1016/0378-1119(94)90764-1
Citation  Kajimoto Y, et al. (1994) Identification of amino-acid polymorphism within the leucine zipper motif of mouse transcription factor A1. Gene 139(2):247-9
abstractText  Mouse transcription factor A1 (A1) is a mouse homologue of human E47, a ubiquitously expressed DNA-binding protein which contains a basic region, helix-loop-helix (HLH) and leucine zipper (LZ) motifs [Walker et al., Nucleic Acids Res. 18 (1990) 1159-1166]. Analyses of the nucleotide (nt) sequences of A1 cDNAs isolated from various mouse strains revealed amino acid (aa) polymorphism in the highly conserved region within the LZ motif. Interestingly, the location and pattern of aa deletions are identical to those previously described for the aa polymorphism within the human counterpart, E47 (E12) [Kamps et al., Cell 60 (1990) 547-555].
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