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Protein Coding Gene : Lin7c lin-7 homolog C, crumbs cell polarity complex component
Primary Identifier  MGI:1330839 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  22343
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable L27 domain binding activity; PDZ domain binding activity; and cytoskeletal protein binding activity. Acts upstream of or within neurotransmitter secretion. Located in synapse. Is active in glutamatergic synapse. Is expressed in brain; brainstem nucleus; and midbrain ventricular layer. Orthologous to human LIN7C (lin-7 homolog C, crumbs cell polarity complex component).
PHENOTYPE: Targeted disruption of this gene appears to have no phenotype, but when combined with Lin7a or Lin7a and Lin7b results in early postnatal lethality. [provided by MGI curators]
  • synonyms:
  • expressed sequence AU019331,
  • MGI:1261877,
  • LIN-7C,
  • expressed sequence AW125731,
  • AW125731,
  • MGI:2138876,
  • RIKEN cDNA 9130007B12 gene,
  • Lin7c,
  • LIN-7-C,
  • DNA segment, Chr 2, ERATO Doi 520, expressed,
  • 9130007B12Rik,
  • MGI:2139318,
  • AI303698,
  • D2Ertd520e,
  • expressed sequence AI303698,
  • MGI:2139174,
  • lin-7 homolog C, crumbs cell polarity complex component,
  • AU019331,
  • MALS-3,
  • MGI:1918822,
  • Veli3
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