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Allele : Plk4<em2Ahol> polo like kinase 4; endonuclease-mediated mutation 2, Andrew Holland
Primary Identifier  MGI:7316651 Allele Type  Endonuclease-mediated
Attribute String  Conditional ready Gene  Plk4
Strain of Origin  (C57BL/6J x SJL/J)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/cas9 genome editing uses two sgRNAs RNAs (mPLK4 sgRNA1: 5'-aagctaggactttaatactc-3', mPLK4 sgRNA2: 5'-ctgcatgtagagggaagctg-3') and ssDNA to introduce two loxP sites into intron 4 and 5.
  • mutations:
  • Insertion
  • synonyms:
  • Plk4<f>,
  • Plk4<f>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele




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