| First Author | Aksenovich TI | Year | 1993 |
| Journal | Genetika | Volume | 29 |
| Issue | 10 | Pages | 1741-9 |
| PubMed ID | 8307363 | Mgi Jnum | J:18055 |
| Mgi Id | MGI:66076 | Citation | Aksenovich TI, et al. (1993) [Planning of samples for linkage analysis. Incomplete penetrance]. Genetika 29(10):1741-9 |
| abstractText | Dependence of the minimal size of a pedigree sample providing the given quality of a linkage decision on the genotype penetrance of the localized gene is considered. The two ways of the sample informativity increase are discussed and their effects are estimated. These ways are: the adequate choice of a marker gene and certain complication of a pedigree structure. It is shown for the latter that the effect can be achieved only for certain phenotypic characteristics of the additional pedigree members. |
