Type | MGI:General | Description | in the F2 generation, 2 of 12 adult transgenic males display a significant reduction in testis size relative to wild-type control littermates (100 ± 0.01 mg vs 229.6 ± 11.23 mg, respectively) in the F3 generation, all adult transgenic males (both fertile and infertile) show a significantly reduced testis size relative to wild-type control littermates (fertile group: 145.03 ± 22.7 mg; infertile group: 81.2 ± 19.7 mg) |