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Protein Coding Gene : Esco1 establishment of sister chromatid cohesion N-acetyltransferase 1

Primary Identifier  MGI:1925055 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  77805
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable identical protein binding activity; peptide-lysine-N-acetyltransferase activity; and zinc ion binding activity. Predicted to be involved in mitotic sister chromatid cohesion and regulation of DNA replication. Predicted to be located in chromosome. Predicted to be part of chromatin. Predicted to be active in nucleus. Is expressed in gonad; reproductive system; and urinary system. Orthologous to human ESCO1 (establishment of sister chromatid cohesion N-acetyltransferase 1).
PHENOTYPE: Mouse embryonic fibroblast homozygous for an activated conditional allele exhibit mitotic arrest in G1. [provided by MGI curators]
  • synonyms:
  • establishment of sister chromatid cohesion N-acetyltransferase 1,
  • A930014I12Rik,
  • RIKEN cDNA A930014I12 gene,
  • Esco1

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