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Allele : Sox17<SHIVA> SRY (sex determining region Y)-box 17; Seric and Hepatic Impaired VAnin

Primary Identifier  MGI:5751535 Allele Type  Chemically induced (ENU)
Gene  Sox17 Inheritance Mode  Dominant
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  ENU mutagenesis induced a T to G substitution leading to a Met72 to Arg change in the DNA binding region of the alpha 1 helix of the HMG domain of Sox17. qRT-PCR and immunoprecipitation confirmed protein expression in adult liver.
  • mutations:
  • Single point mutation
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele