Primary Identifier | MGI:5751535 | Allele Type | Chemically induced (ENU) |
Gene | Sox17 | Inheritance Mode | Dominant |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | ENU mutagenesis induced a T to G substitution leading to a Met72 to Arg change in the DNA binding region of the alpha 1 helix of the HMG domain of Sox17. qRT-PCR and immunoprecipitation confirmed protein expression in adult liver. |