Primary Identifier | MGI:5896795 | Allele Type | Targeted |
Attribute String | Conditional ready | Gene | Smc3 |
Transmission | Germline | Strain of Origin | C57BL/6N |
Is Recombinase | false | Is Wild Type | false |
Project Collection | EUCOMM |
molecularNote | The L1L2_gt1 cassette was inserted at position 53603082 of Chromosome 19 upstream of exon 4 (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of exon 4 at position 53603827. Exon 4 is thus flanked by loxP sites. A "conditional ready" (floxed) allele was created by flp recombinase expression in mice carrying this allele to remove the lacZ sequence and neo selection cassette, leaving loxP sites flanking exon 4. |