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Allele : Del(6Ephb6-Trpv6)2Mfre deletion, Chr 6, Marc Freichel 2

Primary Identifier  MGI:5430774 Allele Type  Targeted
Attribute String  Null/knockout Gene  Del(6Ephb6-Trpv6)2Mfre
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of a exon 13. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 15. Cre-mediated recombination removed exons 13 through 15 of Trpv6, exons 17 and 18 of Ephb6 and the neo cassette. Western blot analysis confirmed the absence of protein expression in the epididymis.
  • mutations:
  • Intergenic deletion,
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Del2Mfre,
  • Ephb6/Trpv6<tm2.1Mfre>,
  • Ephb6/Trpv6<tm2.1Mfre>,
  • Trpv6<->,
  • Del2Mfre,
  • Trpv6<->
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1 Feature

Trail: Allele

Genome

0 Expresses

2 Mutation Involves

Trail: Allele

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele