First Author | Holmes RS | Year | 1976 |
Journal | Biochem Genet | Volume | 14 |
Issue | 11-12 | Pages | 981-7 |
PubMed ID | 13782 | Mgi Jnum | J:5771 |
Mgi Id | MGI:54248 | Doi | 10.1007/BF00485130 |
Citation | Holmes RS (1976) Genetics of peroxisomal enzymes in the mouse: nonlinkage of D-amino acid oxidase locus (Dao) to catalase (Cs) and L-alpha-hydroxyacid oxidase (Hao-1) loci on chromosome 2. Biochem Genet 14(11-12):981-7 |
abstractText | An electrophoretic polymorphism of the peroxisomal enzyme D-amino acid oxidase was observed in NZC strain Mus musculus. F1 (NZC X BALB/c) mice showed a codominant allcle two-banded phenotype which is inconsistent with the dimeric subunit structure reported for this enzyme in other species. The enzyme locus (Dao) was shown to segregate independently of Hao-1, encoding the peroxisomal enzyme hydroxyacid oxidase (liver on A4 isozyme). Thus Dao is not linked to previously mapped peroxisomal enzyme loci, Hao-1 and Cs, closely localized on chromosome 2. |