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Allele : Cdk17<em1(IMPC)J> cyclin dependent kinase 17; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:5912110 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Cdk17
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences CGTCTATGCTCGAGATCCAC, GAGGCACTGTTTACCTTTAA, GCTTGTTTGAAGCATCATGA and TTTTTTCCCTAATTATCCCA, which resulted in a 360 bp deletion beginning at Chromosome 10 positive strand position 93,216,203 bp and ending after 93,216,562 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000574151 (exon 4) and 226 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 94 and early truncation 3 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele