Primary Identifier | MGI:2154093 | Allele Type | QTL |
Gene | Gvhd1 | Inheritance Mode | Recessive |
Strain of Origin | C57BL/10J | Is Recombinase | false |
Is Wild Type | false |
description | Animals homozygous for C57BL/10J-derived alleles at both Gvhd1 and Gvhd2 induced the most severe disease response in F1 recipients. |
molecularNote | In donor animals, this allele confers increased graft versus host disease severity in recipient animals compared to DBA/2J. |