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Allele : Gpx4<tm1Prol> glutathione peroxidase 4; targeted mutation 1, Tomas A Prolla

Primary Identifier  MGI:2651590 Allele Type  Targeted
Attribute String  Null/knockout Gene  Gpx4
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 3 through 7 of the endogenous gene were replaced with an hprt cassette inserted by homologous recombination. Transcript and protein levels were reduced by approximately 50% relative to wild-type levels in heart, liver, kidney, brain, and testes tissues.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Gpx4<->,
  • Gpx4<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

12 Publication categories

Trail: Allele