| First Author | Gariboldi M | Year | 2003 |
| Journal | Carcinogenesis | Volume | 24 |
| Issue | 11 | Pages | 1819-26 |
| PubMed ID | 12919955 | Mgi Jnum | J:85734 |
| Mgi Id | MGI:2676305 | Doi | 10.1093/carcin/bgg133 |
| Citation | Gariboldi M, et al. (2003) Gene expression profile of normal lungs predicts genetic predisposition to lung cancer in mice. Carcinogenesis 24(11):1819-1826 |
| abstractText | Genetic susceptibility to lung tumorigenesis shows large variations among mouse strains. To test whether genetic predisposition to lung tumorigenesis is associated with a specific gene expression profile in normal lungs, we analyzed gene expression in 16 inbred strains of known susceptibility/resistance to lung tumorigenesis, using the RIKEN mouse full-length cDNA 19K microarray set. The strain-specific expression profile of 91 cDNA clones correlated with strain lung tumor susceptibility/resistance and predicted, by principal component analysis, the genetic predisposition to lung tumorigenesis in mice. |
