Primary Identifier | MGI:3793867 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Atxn2 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | An frt-flanked neo cassette with a 3' loxP site was inserted downstream of exon 1 and an additional loxP site was inserted upstream of exon 1. Transient cre expression in ES cells ws used to remove exon 1 and the neo cassette. The absence of protein product was confirmed by western blot analysis on brain extracts. |