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Allele : Mafk<tm1.1Jeng> v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian); targeted mutation 1.1, James Douglas Engel

Primary Identifier  MGI:6324506 Allele Type  Targeted
Attribute String  Reporter Gene  Mafk
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A portion of exon 2 and all of exon 3 were replaced by a cassette inserted downstream of the translational start codon and containing lacZ and floxed neo genes. RNAse protection assays were utilized to confirm the absence of transcript in homozygous mutant mice. Expression of beta-galactosidase was driven by the endogenous promoter. The loxP-flanked neomycin selection cassete was removed via cre-mediated recombination.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele