Primary Identifier | MGI:3687866 | Allele Type | Targeted |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Aqp2 |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The C terminus was exchanged for that of the human AQP2 with a deletion of bp 763-772. A floxed lacZ-neo was included in the vector and subsequently removed via cre-mediated recombination. Western blot detected expression of a chimeric protein in mutant mice. |