Primary Identifier | MGI:3687199 | Allele Type | Targeted |
Attribute String | Conditional ready, Constitutively active, Inserted expressed sequence, Reporter | Gene | Gt(ROSA)26Sor |
Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | An IRES-eGFP cassette and a cDNA sequence encoding Ikbkb containing two serine to glutamate substitutions in the activation loop of the kinase domain, preceded by a floxed stop-neo cassette was inserted into the locus. The Ikbkb would be expressed under the control of the endogenous ROSA26 promoter after cre-mediated excision of the STOP cassette. |