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Allele : Gt(ROSA)26Sor<tm4(Ikbkb)Rsky> gene trap ROSA 26, Philippe Soriano; targeted mutation 4, Klaus Rajewsky

Primary Identifier  MGI:3687199 Allele Type  Targeted
Attribute String  Conditional ready, Constitutively active, Inserted expressed sequence, Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  An IRES-eGFP cassette and a cDNA sequence encoding Ikbkb containing two serine to glutamate substitutions in the activation loop of the kinase domain, preceded by a floxed stop-neo cassette was inserted into the locus. The Ikbkb would be expressed under the control of the endogenous ROSA26 promoter after cre-mediated excision of the STOP cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Gt(ROSA)26Sor<tm1(Ikbkb)Mass>,
  • R26StopIkk2SSEE,
  • R26IKK2ca<sFL>,
  • R26IKK2ca<sFL>,
  • R26StopIkk2SSEE,
  • Gt(ROSA)26Sor<tm1(Ikbkb)Mass>,
  • R26Stop<FL>ikk2ca,
  • R26Stop<FL>ikk2ca
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

45 Publication categories

Trail: Allele