Primary Identifier | MGI:5461488 | Allele Type | Targeted |
Gene | Ngf | Transmission | Germline |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Nucleotide substitutions result in the amino acid substitution of lysine and arginine for two alanines at positions 120 and 121 within the furin recognition site. Cre-mediated recombination removed the FRT- and loxP-flanked neo cassette inserted upstream of the modified exon. An HA-tag was inserted in-frame before the stop codon. |