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Protein Coding Gene : Tctn3 tectonic family member 3
Primary Identifier  MGI:1914840 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  67590
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Involved in cilium assembly. Predicted to be located in nucleus. Is expressed in several structures, including brain and olfactory epithelium. Human ortholog(s) of this gene implicated in Joubert syndrome 18 and orofaciodigital syndrome IV. Orthologous to human TCTN3 (tectonic family member 3).
PHENOTYPE: Homozygous nulls die between E14.5 and E16.5, show holoprosencephaly, polydactyly, randomized heart looping, absent floor plate, and reduced cilia number. [provided by MGI curators]
  • synonyms:
  • expressed sequence AI197391,
  • Tect3,
  • RIKEN cDNA 4930521E07 gene,
  • 4930521E07Rik,
  • Tctn3,
  • AI197391,
  • tectonic family member 3,
  • MGI:2147490
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Features --> Cross References

Genome

Sequence Feature Displayer

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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