| Primary Identifier | MGI:95686 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 14562 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable cytokine activity and protein kinase binding activity. Involved in positive regulation of fat cell differentiation. Acts upstream of or within several processes, including anterior/posterior axis specification; negative regulation of myoblast differentiation; and response to dietary excess. Predicted to be located in cytoplasm. Predicted to be active in extracellular space. Is expressed in several structures, including epiblast; genitourinary system; gut; hemolymphoid system gland; and skeleton. Human ortholog(s) of this gene implicated in Klippel-Feil syndrome 3 and isolated microphthalmia 7. Orthologous to human GDF3 (growth differentiation factor 3). PHENOTYPE: Mice homozygous for a null allele exhibit prenatal lethality and resistance to diet-induced obesity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
