Primary Identifier | MGI:1931862 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Gpr143 |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A PGK-hprt expression cassette replaced exon 1 including the start codon of the gene. Several human mutations are located in the corresponding human exon 1. Northern analysis of primary melanocyte cultures did not detect transcript in homozygous mutant neonates. |