| First Author | Chang CJ | Year | 1992 |
| Journal | DNA Cell Biol | Volume | 11 |
| Issue | 4 | Pages | 315-20 |
| PubMed ID | 1605854 | Mgi Jnum | J:877 |
| Mgi Id | MGI:49410 | Doi | 10.1089/dna.1992.11.315 |
| Citation | Chang CJ, et al. (1992) Structure and expression of mouse alpha 1-acid glycoprotein gene-3 (AGP-3). DNA Cell Biol 11(4):315-20 |
| abstractText | The genome of Mus domesticus has multiple genes of the alpha 1-acid glycoprotein (AGP). Two cDNA clones were identified corresponding to AGP-1 and AGP-2. Moreover, two alleles of AGP-1 exist in inbred mice. The genomic DNA of the AGP-2 gene has been cloned and studied. Here we report the genomic organization of three M. domesticus AGP genes, the sequence analysis of the AGP-3 genomic DNA, and the expression of the AGP-3 gene. The major structural differences between AGP-2 and AGP-3 genes are located in introns 1 and 5. The low level of AGP-3 mRNA can be detected by the polymerase chain reaction (PCR). The molecular basis of the low level expression of AGP-3 and the possible classification of AGP-3 as a pseudogene are discussed. |
