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Allele : Sting1<tm3.1Camb> stimulator of interferon response cGAMP interactor 1; targeted mutation 3.1, John Cambier
Primary Identifier  MGI:6379578 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Sting1
Transmission  Germline Strain of Origin  C57BL/6N-A<tm1Brd>
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting vector is designed to insert an FRT-flanked neomycin resistance (neo) cassette downstream of exon 5 of the gene. Exon 6 was modified to harbor mutation (R231H) equivalent to the most common alternative allelic variant of Sting found in humans (R232H). Flp-mediated recombination removed the FRT-flanked neo cassette.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • STING-R231H,
  • STING-R231H
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

0 Driven By

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Trail: Allele




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