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Allele : Ofd1<tm1Bfra> OFD1, centriole and centriolar satellite protein; targeted mutation 1, Brunella Franco

Primary Identifier  MGI:3620081 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ofd1
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 4 and 5 were flanked by loxP sites via homologous recombination. The Frt flanked neo cassette was removed by Flp recombinase in the ES cells. After Cre mediated recombination RT-PCR confirmed absence of these exons from transcripts in mutants and Western blot analysis failed to detect protein from recombined embryos. This allele was generated from Ofd1tm2.1Bfra
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Ofd1delta4-5,
  • Ofd1delta4-5
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

7 Publication categories

Trail: Allele