Primary Identifier | MGI:6360893 | Allele Type | Targeted |
Attribute String | Inducible, Null/knockout, Recombinase | Gene | Atf3 |
Transmission | Germline | Strain of Origin | 129S/SvEv |
Induced With | tamoxifen | Is Recombinase | true |
Is Wild Type | false |
molecularNote | Thetargeting vector was constructed to insert a construct directly after the ATG start codon of the mouse Atf3 gene containing: Cre fused to the mutated estrogen-ligand binding domain (CreERT2), 1.2 kb of Atf3 3' untranslated region, a Simian virus 40 stop signal and a neomycin cassette flanked by two FLP recognition target sites. The neo cassette was removed from founders by crossing with Flp recombinase mice. It is a null allele. |