| Primary Identifier | MGI:101898 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 18986 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables chromatin binding activity and sequence-specific DNA binding activity. Acts upstream of or within lens induction in camera-type eye; olfactory placode formation; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including cerebellum; embryo ectoderm; genitourinary system; lung; and sensory organ. Orthologous to human POU2F1 (POU class 2 homeobox 1). PHENOTYPE: Homozygous mutation of this gene results in prenatal lethality, with earlier lethality on either a 129/Sv or C57BL/6 background than a mixed 129/Sv and C57BL/6 background. Embryos show decreased erythropoiesis and partial penetrance of small lens size. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
