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Publication : Molecular cloning of the cDNA encoding a receptor tyrosine kinase-related molecule with a catalytic region homologous to c-met.

First Author  Paul SR Year  1992
Journal  Int J Cell Cloning Volume  10
Issue  5 Pages  309-14
PubMed ID  1333503 Mgi Jnum  J:21813
Mgi Id  MGI:69719 Doi  10.1002/stem.5530100509
Citation  Paul SR, et al. (1992) Molecular cloning of the cDNA encoding a receptor tyrosine kinase-related molecule with a catalytic region homologous to c-met. Int J Cell Cloning 10(5):309-14
abstractText  Receptor tyrosine kinases mediate a range of growth and differentiation processes in multiple biological systems. In this work, we report the identification of a novel tyrosine kinase-related molecule, nyk-r, and the molecular cloning of its complete cDNA. Its extra-cellular domain bears no apparent homology with other receptor families, but its intracellular kinase-related region has considerable similarity with members of the insulin-receptor family such as c-met and trk B. Also, the nyk-r gene is expressed in a wide range of tissues and cell lines.
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