First Author | Paul SR | Year | 1992 |
Journal | Int J Cell Cloning | Volume | 10 |
Issue | 5 | Pages | 309-14 |
PubMed ID | 1333503 | Mgi Jnum | J:21813 |
Mgi Id | MGI:69719 | Doi | 10.1002/stem.5530100509 |
Citation | Paul SR, et al. (1992) Molecular cloning of the cDNA encoding a receptor tyrosine kinase-related molecule with a catalytic region homologous to c-met. Int J Cell Cloning 10(5):309-14 |
abstractText | Receptor tyrosine kinases mediate a range of growth and differentiation processes in multiple biological systems. In this work, we report the identification of a novel tyrosine kinase-related molecule, nyk-r, and the molecular cloning of its complete cDNA. Its extra-cellular domain bears no apparent homology with other receptor families, but its intracellular kinase-related region has considerable similarity with members of the insulin-receptor family such as c-met and trk B. Also, the nyk-r gene is expressed in a wide range of tissues and cell lines. |