Primary Identifier | MGI:3045843 | Allele Type | Chemically induced (ENU) |
Gene | Myb | Inheritance Mode | Semidominant |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | As a result of an A to T transversion, this allele has an aspartic acid to valine mutation at residue 384 in the leucine-zipper domain. Northern blot indicates mRNA is expressed at normal levels in hematopoitic tissues but a transactivation assay revealed a significant reduction in protein activity as compared to wild-type. |