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Allele : Myb<Plt4> myeloblastosis oncogene; Plt4

Primary Identifier  MGI:3045843 Allele Type  Chemically induced (ENU)
Gene  Myb Inheritance Mode  Semidominant
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  As a result of an A to T transversion, this allele has an aspartic acid to valine mutation at residue 384 in the leucine-zipper domain. Northern blot indicates mRNA is expressed at normal levels in hematopoitic tissues but a transactivation assay revealed a significant reduction in protein activity as compared to wild-type.
  • mutations:
  • Single point mutation
  • synonyms:
  • c-Myb<Plt4>,
  • c-Myb<Plt4>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

11 Publication categories

Trail: Allele